UPDATE: After the Google panda effect only useless links like comment links should be tagged as nofollow. Links pointing to your post pages should be kept dofollow like labels and archives
Matt Cutts from Google “Webmaster help” has given a detailed video explanation on the use of rel="nofollow" tag and he has paid great stress on the fact that all links that point from one page on your blog to another whether they are hyperlinks or anchor tags must be kept dofollow.
If you have any questions then feel free to post your query. You will also enjoy these SEO tips: